反式-1-苯基-1-戊烯合成路线 （共 108 条）
反应条件
(S)-2-((4-benzyl-1-(2,6-diisopropylphenyl)-4,5-dihydro-1H-imidazol-3-ium-3-yl)methyl)benzenesulfonate in diethyl ether
T=-15°C; Grignard reaction; 17 h; Inert atmosphere; optical yield given as percent eeregioselective reaction;
参考文献
Latham, Christopher M.; Blake, Alexander J.; Lewis, William; Lawrence, Matthew; Woodward, Simon
European Journal of Organic Chemistry, 2012 , # 4 p. 699 - 707
反应条件
(S)-2-((4-benzyl-1-(2,6-diisopropylphenyl)-4,5-dihydro-1H-imidazol-3-ium-3-yl)methyl)benzenesulfonate in diethyl ether
T=-15°C; Grignard reaction; 17 h; Inert atmosphere; optical yield given as percent eeregioselective reaction;
参考文献
Latham, Christopher M.; Blake, Alexander J.; Lewis, William; Lawrence, Matthew; Woodward, Simon
European Journal of Organic Chemistry, 2012 , # 4 p. 699 - 707
反应条件
N,N-dimethyl-formamide dimethyl acetal in chloroform
T=22°C; 20 h; Yield given. Yields of byproduct given;
参考文献
Mulzer, Johann; Bruentrup, Gisela
Chemische Berichte, 1982 , vol. 115, # 6 p. 2057 - 2075
反应条件
lithium aluminium tetrahydride; titanium(III) chloride in tetrahydrofuran
48 h; Heating;
参考文献
Chan, T. H.; Li, J. S.; Aida, T.; Harpp, David N.
Tetrahedron Letters, 1982 , vol. 23, # 8 p. 837 - 840
反应条件
lithium bromide in THF-d8 (tetrahydrofuran-d8)
T=-30°C; Product distributionRate constant;
参考文献
Maryanoff, Bruce E.; Reitz, Allen B.; Mutter, Martin S.; Inners, Ruth R.; Almond, Harold R. Jr.
Journal of the American Chemical Society, 1985 , vol. 107, # 4 p. 1068 - 1070
反应条件
lithium bromide in THF-d8 (tetrahydrofuran-d8)
T=-30°C; Product distributionRate constant;
参考文献
Maryanoff, Bruce E.; Reitz, Allen B.; Mutter, Martin S.; Inners, Ruth R.; Almond, Harold R. Jr.
Journal of the American Chemical Society, 1985 , vol. 107, # 4 p. 1068 - 1070
反应条件
vinyl 1-butyl ether; dirhodium(II) tetrakis(perfluorobutyrate) in benzene
Heating;
参考文献
Doyle, Michael P.; High, Kenneth G.; Oon, Su-Min; Osborn, Antonio K.
Tetrahedron Letters, 1989 , vol. 30, # 23 p. 3049 - 3052
反应条件
sodium hydroxide in dichloromethane; water
T=20°C; Wittig reaction; 0.5 h; Title compound not separated from byproducts.;
参考文献
Al Busafi, Saleh; Al Rawahi, Waffa
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2007 , vol. 46, # 2 p. 370 - 374
反应条件
1: NaNH2 / tetrahydrofuran
2: tetrahydrofuran / 2 h / 25 °C
View Scheme
参考文献
Jeganathan, Suruliappa; Tsukamoto, Masamitsu; Schlosser, Manfred
Synthesis, 1990 , # 2 p. 109 - 111
反应条件
1: 97 percent / pyridine,NaHCO3 / ethanol / 0.33 h / 70 °C
2: NaNH2 / tetrahydrofuran
3: tetrahydrofuran / 2 h / 25 °C
View Scheme
参考文献
Jeganathan, Suruliappa; Tsukamoto, Masamitsu; Schlosser, Manfred
Synthesis, 1990 , # 2 p. 109 - 111
