反应条件
1: sulfuric acid / 24 h / Reflux
2: palladium 10 on activated carbon; hydrogen / methanol / 24 h / 20 °C
3: 1H-imidazole / N,N-dimethyl-formamide / 3 h / 20 °C
4: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / -15 °C
5: 4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide / dichloromethane / 4 h / 20 °C
6: tetrabutyl ammonium fluoride / tetrahydrofuran / Inert atmosphere
View Scheme
参考文献
Lee, Eunyoung; Jamal Ahamed; Kumar, Mahto Sanjeev; Rhee, Seog Woo; Moon, Surk-Sik; Hong, In Seok
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 21 p. 6245 - 6248