S(+)-2-氨基-3-(甲基氨基)丙酸盐酸盐合成路线 （共 4 条）
反应条件
1: C28H25Cl2N3NiO4 With acetic anhydride; sodium carbonate in acetonitrile T=25 - 70°C; 2: N-methylamine hydrochloride With potassium carbonate in acetonitrile T=50°C; Michael condensation; 6 h; 3: With hydrogenchloride; water in ethanol
参考文献
Saghiyan, Ashot S.; Stepanyan, Lala A.; Manasyan, Luiza L.; Geolchanyan, Arpine V.; Djamgaryan, Silva M.; Ajvazyan, Hrant R.; Panosyan, Henry A.; Maleev, Viktor I.; Saveleva, Tatiana F.
Tetrahedron Asymmetry, 2010 , vol. 21, # 21-22 p. 2638 - 2645
反应条件
1: C30H31N3NiO4 With acetic anhydride; sodium carbonate in acetonitrile T=25 - 70°C; 2: N-methylamine hydrochloride With potassium carbonate in acetonitrile T=50°C; Michael condensation; 6 h; 3: With hydrogenchloride; water in ethanol
参考文献
Saghiyan, Ashot S.; Stepanyan, Lala A.; Manasyan, Luiza L.; Geolchanyan, Arpine V.; Djamgaryan, Silva M.; Ajvazyan, Hrant R.; Panosyan, Henry A.; Maleev, Viktor I.; Saveleva, Tatiana F.
Tetrahedron Asymmetry, 2010 , vol. 21, # 21-22 p. 2638 - 2645
反应条件
1: C28H26ClN3NiO4 With acetic anhydride; sodium carbonate in acetonitrile T=25 - 70°C; 2: N-methylamine hydrochloride With potassium carbonate in acetonitrile T=50°C; Michael condensation; 1.5 h; 3: With hydrogenchloride; water in ethanol
参考文献
Saghiyan, Ashot S.; Stepanyan, Lala A.; Manasyan, Luiza L.; Geolchanyan, Arpine V.; Djamgaryan, Silva M.; Ajvazyan, Hrant R.; Panosyan, Henry A.; Maleev, Viktor I.; Saveleva, Tatiana F.
Tetrahedron Asymmetry, 2010 , vol. 21, # 21-22 p. 2638 - 2645
反应条件
1: C28H26FN3NiO4 With acetic anhydride; sodium carbonate in acetonitrile T=25 - 70°C; 2: N-methylamine hydrochloride With potassium carbonate in acetonitrile T=50°C; Michael condensation; 3.5 h; 3: With hydrogenchloride; water in ethanol
参考文献
Saghiyan, Ashot S.; Stepanyan, Lala A.; Manasyan, Luiza L.; Geolchanyan, Arpine V.; Djamgaryan, Silva M.; Ajvazyan, Hrant R.; Panosyan, Henry A.; Maleev, Viktor I.; Saveleva, Tatiana F.
Tetrahedron Asymmetry, 2010 , vol. 21, # 21-22 p. 2638 - 2645
