7-氯-1,2,3,4-四氢苯并[b]氮杂卓-5-酮合成路线 （共 13 条）
反应条件
caesium acetate; 1,8-diazabicyclo[5.4.0]undec-7-ene; triphenylphosphine; palladium diacetate in N,N-dimethyl-formamide Heating;
参考文献
Torisawa, Yasuhiro; Furuta, Takuya; Nishi, Takao; Aki, Shinji; Minamikawa, Jun-ichi
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 23 p. 6455 - 6458
反应条件
1: 32 percent / Et3N / CH2Cl2 / 2 h / 20 °C 2: 39 percent / SnCl2*2H2O; conc. HCl / ethanol / 20 °C 3: 53 percent / Et3N / CH2Cl2 / 1.5 h / 20 °C View Scheme
参考文献
HETERO RESEARCH FOUNDATION; Reddy, Bandi Parthasaradhi; Reddy, Kura Rathnakar; Reddy, Dasari Muralidhara; Reddy, Maruthi Janakiram; Krishna, Bandi Vamsi
Patent: US2013/190490 A1, 2013 ;
反应条件
1: 32 percent / Et3N / CH2Cl2 / 2 h / 20 °C 2: 39 percent / SnCl2*2H2O; conc. HCl / ethanol / 20 °C 3: 53 percent / Et3N / CH2Cl2 / 1.5 h / 20 °C 4: 30 percent / NaBH4 / methanol / 1 h / 20 °C View Scheme
参考文献
HETERO RESEARCH FOUNDATION; Reddy, Bandi Parthasaradhi; Reddy, Kura Rathnakar; Reddy, Dasari Muralidhara; Reddy, Maruthi Janakiram; Krishna, Bandi Vamsi
Patent: US2013/190490 A1, 2013 ;
