2-甲基-5,6-二氢-4H-吡喃合成路线 （共 26 条）
反应条件
(i) (bromination), (ii) /BRN= 3587200/, Et2O, (iii) Na; Multistep reaction;
参考文献
LeBel,N.A.; Banucci,E.G.
Journal of Organic Chemistry, 1971 , vol. 36, p. 2440 - 2448
反应条件
1: 80 percent / HCl / 0.25 h / 0 °C
2: 58 percent / NaH / tetrahydrofuran / 2 h / Ambient temperature
View Scheme
参考文献
Briggs, Andrew J.; Evans, Christopher M.; Glenn, Robert; Kirby, Anthony J.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1983 , # 11 p. 1637 - 1640
反应条件
1: 80 percent / HCl / 0.25 h / 0 °C
2: 68 percent / NaH / tetrahydrofuran / 2 h / Ambient temperature
View Scheme
参考文献
Briggs, Andrew J.; Evans, Christopher M.; Glenn, Robert; Kirby, Anthony J.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1983 , # 11 p. 1637 - 1640
反应条件
1: 80 percent / HCl / 0.25 h / 0 °C
2: NaH / tetrahydrofuran / 2 h / Ambient temperature
View Scheme
参考文献
Briggs, Andrew J.; Evans, Christopher M.; Glenn, Robert; Kirby, Anthony J.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1983 , # 11 p. 1637 - 1640
反应条件
hydrogenchloride
T=0°C; 0.25 h;
参考文献
Briggs, Andrew J.; Evans, Christopher M.; Glenn, Robert; Kirby, Anthony J.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1983 , # 11 p. 1637 - 1640
反应条件
1: chlorine
2: sodium; diethyl ether
3: toluene-4-sulfonyl chloride; pyridine / und Erwaermen des Reaktionsprodukts mit Natriumjodid in Aceton
View Scheme
参考文献
Ansell; Brown
Journal of the Chemical Society, 1957 , p. 1788,1793
