1-(4-氯苯磺酰基)-哌嗪合成路线 (共 3 条)
反应条件
1: triethylamine / dichloromethane / 48 h / 20 °C 2: hydrogenchloride; acetic acid / water / 2 h / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 54, # 8 p. 3086 - 3090
反应条件
hydrogenchloride in water; dimethyl sulfoxide T=25°C; Kinetics;
参考文献
Journal of Organic Chemistry, , vol. 69, # 9 p. 3166 - 3172
反应条件
dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; triethylsilane; triethylamine; bis(dibenzylideneacetone)-palladium(0) in 1,4-dioxane T=100°C; 16 h; Inert atmosphere;
参考文献
Noonan, Gary M.; Hayter, Barry R.; Campbell, Andrew D.; Gorman, Timothy W.; Partridge, Benjamin E.; Lamont, Gill M.
Tetrahedron Letters, 2013 , vol. 54, # 34 p. 4518 - 4521