5-甲氧基-2-甲基-1,3-二硝基苯合成路线 （共 15 条）
反应条件
sodium 2 h; Heating;
参考文献
Buechi, George; Lee, Gary C. M.; Yang, David; Tannenbaum, Steven R.
Journal of the American Chemical Society, 1986 , vol. 108, # 14 p. 4115 - 4119
反应条件
T=20°C; 2 h; Heating / reflux;
参考文献
Serafinowski, Pawel J.; Garland, Peter B.
Organic and Biomolecular Chemistry, 2008 , vol. 6, # 18 p. 3284 - 3291
反应条件
1: 45 percent / fuming nitric acid, fuming sulfuric acid / 6 h / 80 - 90 °C 2: 57 percent / sodium / 2 h / Heating View Scheme
参考文献
Buechi, George; Lee, Gary C. M.; Yang, David; Tannenbaum, Steven R.
Journal of the American Chemical Society, 1986 , vol. 108, # 14 p. 4115 - 4119
参考文献
Pailer,M.; Bergthaller,P.
Monatshefte fuer Chemie, 1967 , vol. 98, # 3 p. 579 - 591
反应条件
1: aqueous H2SO4 / <0 / Diazotization.Eintragen der Diazoniumsalz-Loesung in siedende wss. CuSO4-Loesung 2: aqueous KOH View Scheme
参考文献
Curd; Robertson
Journal of the Chemical Society, 1933 , p. 437,440
反应条件
1: With pyrrolidine in DMF (N,N-dimethyl-formamide) T=120°C; 2: With hydrogen; palladium 10 on activated carbon in benzene P=2585.81 Torr;
参考文献
EP1147083 B1, ;
Page 50 ;
EP 1147083 B1
反应条件
1: 35 percent / sodium bicarbonate, sodium sulfide nonahydrate / H2O / 1 h / Heating 2: 58 percent / 1.) sodium nitrite, 12M HCl; 2.) copper(I) chloride / H2O / 0 - 5 °C / 2.) 10 min 3: 1.) pyrrolydine; 2.) H2 / 2.) 5percent palladium on charcoal / 1.) DMF, reflux, 3 h; 2.) 4 atm View Scheme
参考文献
Buechi, George; Lee, Gary C. M.; Yang, David; Tannenbaum, Steven R.
Journal of the American Chemical Society, 1986 , vol. 108, # 14 p. 4115 - 4119
反应条件
1: SnCl2, HCl 2: (i) aq. NaNO2, H2SO4, (ii) CuSO4 3: K2CO3 / dimethylformamide View Scheme
参考文献
Pailer,M.; Bergthaller,P.
Monatshefte fuer Chemie, 1967 , vol. 98, # 3 p. 579 - 591
反应条件
1: 35 percent / sodium bicarbonate, sodium sulfide nonahydrate / H2O / 1 h / Heating 2: 58 percent / 1.) sodium nitrite, 12M HCl; 2.) copper(I) chloride / H2O / 0 - 5 °C / 2.) 10 min View Scheme
参考文献
Buechi, George; Lee, Gary C. M.; Yang, David; Tannenbaum, Steven R.
Journal of the American Chemical Society, 1986 , vol. 108, # 14 p. 4115 - 4119
反应条件
sodium sulfide; sodium hydrogencarbonate in water 1 h; Heating;
参考文献
Buechi, George; Lee, Gary C. M.; Yang, David; Tannenbaum, Steven R.
Journal of the American Chemical Society, 1986 , vol. 108, # 14 p. 4115 - 4119
