disodium hydrogenphosphate; 3-chloro-benzenecarboperoxoic acid in dichloromethane T=20°C; 1 h;

1: 1.) 60percent NaH / 1.) DMF, 0 deg C, 15 min, 2.) DMF, 4 deg C, 15 min 2: AlCl3 / 1.) 1,2-dichloroethane, 0 deg C, 20 min then 20 deg C, 2.) 1,2-dichloroethane, 20 deg C, 15 min 3: 80 percent / m-CPBA (80percent), Na2HPO4 / CH2Cl2 / 1 h / 20 °C View Scheme

1: AlCl3 / 1.) 1,2-dichloroethane, 0 deg C, 20 min then 20 deg C, 2.) 1,2-dichloroethane, 20 deg C, 15 min 2: 80 percent / m-CPBA (80percent), Na2HPO4 / CH2Cl2 / 1 h / 20 °C View Scheme

1: 1.) 60percent NaH / 1.) DMF, 0 deg C, 15 min, 2.) DMF, 4 deg C, 15 min 2: AlCl3 / 1.) 1,2-dichloroethane, 0 deg C, 20 min then 20 deg C, 2.) 1,2-dichloroethane, 20 deg C, 15 min 3: 80 percent / m-CPBA (80percent), Na2HPO4 / CH2Cl2 / 1 h / 20 °C View Scheme

1: 96 percent / 15percent aq. NaSMe / methanol / 2 h / 20 °C 2: 68 percent / 60percent NaH / dimethylformamide / 0.17 h / -20 °C View Scheme

sodium thiomethoxide in methanol T=20°C; 2 h;