2-氨基-5-甲基吡啶合成路线 （共 125 条）
反应条件
in methanol; acetone
参考文献
The United States of America as represented by the Secretary of the Army
Patent: US5204352 A1, 1993 ;
反应条件
in ethanol 24 h; Heating;
参考文献
Klupsch, Frederique; Houssin, Raymond; Humbert, Luc; Imbenotte, Michel; Henichart, Jean-Pierre; Lhermitte, Michel
Chemical and Pharmaceutical Bulletin, 2006 , vol. 54, # 9 p. 1318 - 1321
反应条件
1: 45 percent / aq. HBF4; NaNO2 / 1 h / 0 - 50 °C 2: NBS; benzoyl peroxide / CCl4 / 2 h / Heating View Scheme
参考文献
Liu, Yuxiu; Zhao, Qiqi; Wang, Qingmin; Li, Heng; Huang, Runqiu; Li, Yonghong
Journal of Fluorine Chemistry, 2005 , vol. 126, # 3 p. 345 - 348
反应条件
1: 92 percent / CH2Cl2 / 12 h / 25 °C 2: 1.) aq. sodium hydroxide, 2.) hydrochloric acid (pH 2) / 1.) 25 deg C, 48 h, 2.) 0 deg C --> 25 deg C, 2 h 3: aq. sodium hydroxide / aq. ethanol / 2 h / Heating View Scheme
参考文献
Katritzky, Alan R.; Awartani, Radi
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 11 p. 2623 - 2627
反应条件
1.1: nitric acid; sulfuric acid / 2 h / 0 - 5 °C 1.2: 4 h / Cooling with ice 2.1: trichlorophosphate / 5 h / Reflux 3.1: sodium dichromate; sulfuric acid / 12 h / 25 °C / Cooling with ice View Scheme
参考文献
Beijing Yiling Bioengineering Co., Ltd.
Patent: EP2366691 A1, 2011 ;
参考文献
Stanovnik, Branko; Svete, Jurij; Tisler, Miha; Zorz, Lilijana; Hvala, Ales; Simonic, Igor
Heterocycles, 1988 , vol. 27, # 4 p. 903 - 910
反应条件
2: |Microwave irradiation; |Heating View Scheme
参考文献
Gomez-Garcia, Omar; Salgado-Zamora, Hector; Campos-Aldrete, Elena
Heterocyclic Communications, 2014 , vol. 20, # 1 p. 21 - 23
反应条件
selenium; triethylamine in toluene T=130°C; 4 h;
参考文献
Ling, Gang; Chen, Jingzhu; Lu, Shiwei
Journal of Chemical Research - Part S, 2003 , # 7 p. 442 - 444
反应条件
in 1,4-dioxane 24 h; Ambient temperature;
参考文献
Sudha, L. V.; Sathyanarayana, D. N.
Journal of Molecular Structure, 1985 , vol. 131, p. 141 - 146
反应条件
Montmorillonite K10; RhCl(PPh3)3 in toluene T=110°C; 2 h; Product distribution;
参考文献
Tetrahedron Letters, , vol. 44, # 8 p. 1631 - 1634
