2-(4-甲氧基苯基)-喹啉合成路线 （共 38 条）
反应条件
potassium phosphate; [1,3-bis(diphenylphosphino) propane] dichloronickel(II) in 1,4-dioxane T=100 - 110°C; Suzuki coupling; Inert atmosphere;
参考文献
Chen, Guo-Jun; Han, Fu-She
European Journal of Organic Chemistry, 2012 , # 19 p. 3575 - 3579
反应条件
CoCl2 in tetrahydrofuran; diethyl ether T=-40°C; 24 h;
参考文献
Korn, Tobias J.; Schade, Matthias A.; Cheemala, Murthy N.; Wirth, Stefan; Guevara, Simon A.; Cahiez, Gerard; Knochel, Paul
Synthesis, 2006 , # 21 p. 3547 - 3574
反应条件
1: 2-hydroxyquinoline With potassium carbonate; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate in 1,4-dioxane T=100°C; 3 h; Inert atmosphere; 2: (4-methoxyphenyl)-boronic acid With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in 1,4-dioxane; water T=100°C; Suzuki-Miyaura coupling; Inert atmosphere;
参考文献
Li, Shui-Ming; Huang, Jie; Chen, Guo-Jun; Han, Fu-She
Chemical Communications, 2011 , vol. 47, # 48 p. 12840 - 12842
反应条件
LiBr*H2O; palladium dichloride in acetonitrile T=60°C; 8 h;
参考文献
Ji, Xiaochen; Huang, Huawen; Li, Yibiao; Chen, Huoji; Jiang, Huanfeng
Angewandte Chemie - International Edition, 2012 , vol. 51, # 29 p. 7292 - 7296
反应条件
1: With N,N,N',N,-tetramethylethylenediamine in toluene T=50°C; 10 h; Inert atmosphere; 2: With water; ammonium chloride in toluene 12 h;
参考文献
Zhuo, Fang-Fang; Xie, Wen-Wen; Yang, Yong-Xin; Zhang, Lei; Wang, Pei; Yuan, Rui; Da, Chao-Shan
Journal of Organic Chemistry, 2013 , vol. 78, # 7 p. 3243 - 3249
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in ethanol; water; toluene Suzuki coupling; 24 h; RefluxInert atmosphere;
参考文献
Lord, Anna-Marie; Mahon, Mary F.; Lloyd, Matthew D.; Threadgill, Michael D.
Journal of Medicinal Chemistry, 2009 , vol. 52, # 3 p. 868 - 877
反应条件
sodium ethanolate in ethanol 5 h; Heating;
参考文献
Kundu, Nitya G.; Mahanty, Jyan S.; Das, Palas; Das, Biswajit
Tetrahedron Letters, 1993 , vol. 34, # 10 p. 1625 - 1628
反应条件
zinc dibromide in chloroform T=90 - 100°C; Diels-Alder reaction; 2 h;
参考文献
Koyama, Junko; Toyokuni, Izumi; Tagahara, Kiyoshi
Chemical and Pharmaceutical Bulletin, 1999 , vol. 47, # 7 p. 1038 - 1039
反应条件
tetracarbonylbis(μ-chloro)dirhodium(I) in toluene T=175°C; 24 h; Inert atmosphereSealed tube;
参考文献
Berman, Ashley M.; Bergman, Robert G.; Ellman, Jonathan A.
Journal of Organic Chemistry, 2010 , vol. 75, # 22 p. 7863 - 7868
反应条件
1: 62 percent / Et3N; CuI / (Ph3P)2PdCl2 / 24 h / 20 °C 2: 63.5 percent / sodium ethoxide / ethanol / 5 h / Heating View Scheme
参考文献
Kundu, Nitya G.; Mahanty, Jyan S.; Das, Palas; Das, Biswajit
Tetrahedron Letters, 1993 , vol. 34, # 10 p. 1625 - 1628
