2-[5-[2-[4-(1,2-苯并异噻唑-3-基)-1-哌嗪基]乙基]-4-氯-2-硝基苯基]-丙二酸1,3-二甲酯合成路线 （共 2 条）
反应条件
1: 95 percent / aq. HCl / 20 h / Heating 2: 94 percent / thionyl chloride / 3 h / Heating 3: 1.) sodium hydrosulfite, 2.) aq. HCl / 1.) THF, ethanol, water, steam bath, 4 h, 2.) THF, ethanol, 15 min, steam bath View Scheme
参考文献
Urban, Frank J.; Breitenbach, Ralph; Gonyaw, Dianne
Synthetic Communications, 1996 , vol. 26, # 8 p. 1629 - 1638
反应条件
1: 95 percent / aq. HCl / 20 h / Heating 2: 94 percent / thionyl chloride / 3 h / Heating 3: 1.) sodium hydrosulfite, 2.) aq. HCl / 1.) THF, ethanol, water, steam bath, 4 h, 2.) THF, ethanol, 15 min, steam bath View Scheme
参考文献
Urban, Frank J.; Breitenbach, Ralph; Gonyaw, Dianne
Synthetic Communications, 1996 , vol. 26, # 8 p. 1629 - 1638
