4-(1H-吡唑-1-甲基)苯甲酸合成路线 （共 5 条）
反应条件
potassium hydroxide in ethanol 3 h; Heating;
参考文献
Silvestri; Pagnozzi; Valoti; Fusi
Farmaco, 1994 , vol. 49, # 10 p. 625 - 632
反应条件
potassium carbonate in acetonitrile
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 4 p. 719 - 722
反应条件
1: 1.) 18-crown-6, KOC(CH3)3 / 1.) diethyl ether, 15 min; 2.) diethyl ether, 2 h at 0°C then overnight at room temp. 2: 86 percent / 10percent aq. KOH / ethanol / 3 h / Heating View Scheme
参考文献
Farmaco, , vol. 49, # 10 p. 625 - 632
反应条件
lithium hydroxide hydrate T=20°C; 18 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 19 p. 5957 - 5960
反应条件
1: potassium carbonate / dimethyl sulfoxide / 72 h / 80 °C 2: lithium hydroxide hydrate / 18 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 19 p. 5957 - 5960
