2,2-二甲基-3-(甲基氨基)-1-丙醇合成路线 （共 8 条）
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=0°C; 22 h; Reflux; 2: With water; sodium hydroxide in tetrahydrofuran; diethyl ether T=0 - 20°C; 6 h;
参考文献
CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO); MCNEENEY, Stephen, Phillip; PASTOR FERNÁNDEZ, Joaquín; MARTÍNEZ GONZÁLES, Sonia; MARTÍN HERNANDO, José Ignacio; RODRÍGUEZ HERGUETA, Antonio; RICO FERREIRA, María del Rosario; BLANCO APARICIO, Carmen
Patent: WO2013/4984 A1, 2013 ;
Location in patent: Page/Page column 67 ;
反应条件
sodium tetrahydroborate in diethyl ether
参考文献
Edmundson, R. S.
Organic Mass Spectrometry, 1982 , vol. 17, # 11 p. 558 - 564
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 96 h; Heating;
参考文献
Huang, Yande; Yu, Jaehoon; Bentrude, Wesley G.
Journal of Organic Chemistry, 1995 , vol. 60, # 15 p. 4767 - 4773
反应条件
hydrogenchloride; hydrogen; platinum in ethanol
参考文献
Journal of Organic Chemistry, , vol. 33, # 5 p. 2123 - 2126
反应条件
1: diethyl ether 2: 57 percent / LiAlH4 / tetrahydrofuran / 96 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 60, # 15 p. 4767 - 4773
反应条件
1: SOCl2 / 50 - 55 °C 2: diethyl ether 3: 57 percent / LiAlH4 / tetrahydrofuran / 96 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 60, # 15 p. 4767 - 4773
参考文献
Bulletin de la Societe Chimique de France, , vol. <4>47, p. 869
反应条件
1.1: sodium carbonate; sodium hydrogencarbonate / tetrahydrofuran; water / 24 h / 0 - 20 °C 2.1: lithium aluminium tetrahydride / tetrahydrofuran / 22 h / 0 °C / |Reflux 2.2: 6 h / 0 - 20 °C View Scheme
