2-(4-硝基苯基)-4H-3,1-苯并恶嗪-4-酮合成路线 (共 17 条)
反应条件
1: thionyl chloride / dichloromethane / 2 h / 20 °C 2: dichloromethane / 20 h / 20 °C 3: water; sodium hydroxide / dichloromethane; methanol / |Reflux 4: thionyl chloride / 2 h / |Reflux View Scheme
参考文献
Prashanth; Revanasiddappa
Medicinal Chemistry Research, 2013 , vol. 22, # 6 p. 2665 - 2676
反应条件
lt;(chlorosulfinyloxy)methylenegt;dimethylammonium chloride; triethylamine 1.) CH2Cl2, 0-5 deg C, 10 min, 2.) CH2Cl2, RT, overnight; Yield given. Multistep reaction;
参考文献
Ramana, D. V.; Kantharaj, E.
Organic Preparations and Procedures International, 1993 , vol. 25, # 5 p. 588 - 590
反应条件
hydrazine hydrate in xylene
2 h; Heating;
参考文献
Reddy, Ch. K.; Reddy, P. S. N.; Ratnam, C. V.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1985 , vol. 24, p. 902 - 904
反应条件
1: 80 percent / hydrazine hydrate / xylene / 0.08 h / Heating
2: 70 percent / xylene / 2 h / Heating
View Scheme
参考文献
Reddy, Ch. K.; Reddy, P. S. N.; Ratnam, C. V.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1985 , vol. 24, p. 902 - 904
反应条件
hydrazine hydrate in benzene
5 h; Reflux;
参考文献
Khan, Mahmud Tareq Hassan; Khan, Rasool; Wuxiuer, Yimingjiang; Arfan, Mohammad; Ahmed, Manzoor; Sylte, Ingebrigt
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 12 p. 4317 - 4327
反应条件
tetraphosphorus decasulfide; TEA in acetonitrile
24 h; Ambient temperature;
参考文献
Dash, Bhabagrahi; Dora, E. Khalli; Panda, Chandra Sekhar
Heterocycles, 1982 , vol. 19, # 11 p. 2093 - 2098
参考文献
Bain,D.I.; Smalley,R.K.
Journal of the Chemical Society [Section] C: Organic, 1968 , p. 1593 - 1597