4,4,4,4',4',4'-六氟-DL-缬氨酸合成路线 （共 9 条）
反应条件
hydrogen; palladium in methanol
参考文献
Hsieh -h.; Needleman; Marshall
Journal of Medicinal Chemistry, 1987 , vol. 30, # 6 p. 1097 - 1100
反应条件
hydrogenchloride 7 h; Heating;
参考文献
Arai, Toru; Imachi, Takashi; Kato, Tamaki; Ogawa, H. Iyehara; Fujimoto, Tsutomu; Nishino, Norikazu
Bulletin of the Chemical Society of Japan, 1996 , vol. 69, # 5 p. 1383 - 1389
反应条件
1: 91 percent / NH3 (liq.) / diethyl ether / a) -80 deg C, 45 min, b) RT, overnight 2: 78 percent / H2 / Pd / methanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 6 p. 1097 - 1100
反应条件
1: 86 percent / NH3 / diethyl ether / 195 - 293 °C 2: 91 percent / 6M aq. HCl / 7 h / Heating View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 69, # 5 p. 1383 - 1389
反应条件
hydrogen; 10 palladium on active carbon
参考文献
Journal of Medicinal Chemistry, , vol. 24, # 9 p. 1043 - 1047
反应条件
1: NH3 / diethyl ether 2: aq. HCl View Scheme
参考文献
Doklady Chemistry, , vol. 133, p. 933 - 936
Doklady Akademii Nauk SSSR, , vol. 133, # 5 p. 1113 - 1116
反应条件
1: K2CO3 2: NH3 / diethyl ether 3: aq. HCl View Scheme
参考文献
Doklady Chemistry, , vol. 133, p. 933 - 936
Doklady Akademii Nauk SSSR, , vol. 133, # 5 p. 1113 - 1116
参考文献
Doklady Chemistry, , vol. 133, p. 933 - 936
Doklady Akademii Nauk SSSR, , vol. 133, # 5 p. 1113 - 1116
反应条件
1: H2SO4 2: NH3 3: aq. HCl View Scheme
参考文献
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), , p. 2002 - 2006
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , # 12 p. 2162 - 2167
