3-氨基-1-苯基-1H-吡唑-4-羧酸乙酯合成路线 （共 3 条）
反应条件
trans-N,N'-dimethylcyclohexane-1,2-diamine; potassium phosphate; copper(l) iodide in 1,4-dioxane T=110°C; Ullmann type arylation; 48 h; Inert atmosphere; regioselective reaction;
参考文献
Deprez-Poulain, Rebecca; Cousaert, Nicolas; Toto, Patrick; Willand, Nicolas; Deprez, Benoit
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 9 p. 3867 - 3876
反应条件
in xylene 72 h; Heating;
参考文献
Massa; Mai; Artico; Corelli
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 6 p. 1805 - 1808
反应条件
1: hydrazine hydrate / ethanol / 6 h / 20 °C 2: trans-N,N'-dimethylcyclohexane-1,2-diamine; copper(l) iodide; potassium phosphate / 1,4-dioxane / 48 h / 110 °C / Inert atmosphere View Scheme
参考文献
Deprez-Poulain, Rebecca; Cousaert, Nicolas; Toto, Patrick; Willand, Nicolas; Deprez, Benoit
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 9 p. 3867 - 3876
