5-氨基-4-乙氧羰基-1-苯基吡唑合成路线 （共 44 条）
反应条件
1: 48 percent / TEA / benzene / 1 h / Heating 2: 96 percent / hydrazine hydrate / 2 h / Heating 3: 45 percent / 8 h / Heating View Scheme
参考文献
Wamhoff, Heinrich; Ertas, Muemtaz; Atta, Sanaa M. S.
Liebigs Annalen der Chemie, 1985 , # 9 p. 1910 - 1916
反应条件
potassium hydroxide 1.) CH2Cl2, 1 h, room temp., 2.) 1 h, reflux; Yield given. Multistep reaction;
参考文献
Wamhoff, Heinrich; Ertas, Muemtaz
Synthesis, 1985 , # 2 p. 190 - 194
参考文献
Schmidt; Druey
Helvetica Chimica Acta, 1956 , vol. 39, p. 986,988
反应条件
0.166667 h; microwave irradiation;
参考文献
Heravi, Majid M.; Nami, Navabeh; Seifi, Nasim; Oskooie, Hossein A.; Hekmatshoar, Rahim
Phosphorus, Sulfur and Silicon and the Related Elements, 2006 , vol. 181, # 3 p. 591 - 599
反应条件
1: 90 percent / AcOH / 3 h / Heating 2: 94 percent / aq. NaOH / ethanol / 1.5 h / Heating View Scheme
参考文献
Corelli; Massa; Stefancich; Silvestri; Artico; Pantaleoni; Palumbo; Fanini; Giorgi
Farmaco, Edizione Scientifica, 1988 , vol. 43, # 3 p. 251 - 265
反应条件
1: 2.) aq. KOH / 1.) 8 h, 210-215 deg C, 2.) 45 min 2: 70 percent / thionyl chloride / benzene / 4 h / Heating View Scheme
参考文献
Plescia, Salvatore; Bajardi, Maria Luisa; Daidone, Giuseppe; Roccaro, Angela
Heterocycles, 1988 , vol. 27, # 1 p. 105 - 112
反应条件
1: 87 percent / acetic acid / 1 h 2: 100 percent / LiAlH4 / tetrahydrofuran / 2 h / Ambient temperature 3: 74 percent / PCl5 / CHCl3 / 0 deg C, 15 min; r.t., 1 h 4: 91 percent / acetonitrile / 3 h / Ambient temperature 5: 100 percent / 10percent KOH / ethanol / 1.25 h / 90 °C View Scheme
参考文献
Corelli; Massa; Stefancich; Silvestri; Artico; Pantaleoni; Palumbo; Fanini; Giorgi
Farmaco, Edizione Scientifica, 1988 , vol. 43, # 3 p. 251 - 265
反应条件
1: 66 percent / 5 h / Heating
2: 95 percent / hydrazine hydrate / ethanol / 0.25 h / Ambient temperature
View Scheme
参考文献
Wamhoff, Heinrich; Ertas, Muemtaz; Atta, Sanaa M. S.
Liebigs Annalen der Chemie, 1985 , # 9 p. 1910 - 1916
参考文献
Ghorab, Mostafa M.; Ragab, Fatma A.; Alqasoumi, Saleh I.; Alafeefy, Ahmed M.; Aboulmagd, Sarah A.
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 1 p. 171 - 178
