5-氨基-4-乙氧羰基-1-苯基吡唑合成路线 （共 44 条）
反应条件
hydrogenchloride; sodium nitrite; sulfur dioxide
1) < 10 deg C, 10 min, 2) CCl4, room temp., 1 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Yamamoto, Susumu; Morimoto, Katsushi; Sato, Toshiaki
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 6 p. 1545 - 1547
反应条件
1: trichlorophosphate / |Cooling with ice; |Microwave irradiation
2: isopropyl alcohol / 0.75 h / |Microwave irradiation
View Scheme
参考文献
Jain, Kishor S.; Khedkar, Vijay M.; Arya, Nikhilesh; Rane, Prasad V.; Chaskar, Pratip K.; Coutinho, Evans C.
European Journal of Medicinal Chemistry, 2014 , vol. 77, p. 166 - 175
反应条件
trichlorophosphate
Vilsmeier-Haack Formylation; Cooling with iceMicrowave irradiation;
参考文献
Jain, Kishor S.; Khedkar, Vijay M.; Arya, Nikhilesh; Rane, Prasad V.; Chaskar, Pratip K.; Coutinho, Evans C.
European Journal of Medicinal Chemistry, 2014 , vol. 77, p. 166 - 175
反应条件
1: 75 percent / NaOH / ethanol / 2 h / Heating
2: 70 percent / 2 h / Heating
View Scheme
参考文献
Pathak, U. S.; Gandhi, Sudha; Rathod, I. S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1994 , vol. 33, # 8 p. 734 - 737
