反应条件
1.1: Jone's reagent / acetone
2.1: chloro-trimethyl-silane / 20 °C
3.1: sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0 °C
4.1: (S,S)-(salen)Co(III)(AcO); water / diethyl ether / 72 h / 0 - 20 °C
5.1: 1H-imidazole; triethylamine / N,N-dimethyl-formamide / 0 - 20 °C
6.1: hydrogen / hexane
7.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane
8.1: benzene / 70 °C
9.1: chromium dichloride / tetrahydrofuran / 0 °C
10.1: piperidine; copper(l) iodide; tetrakis(triphenylphosphine) palladium(0) / benzene / 20 °C
11.1: pyridinium p-toluenesulfonate / methanol / 0 °C
12.1: copper/silver activated zinc; water / methanol / 16 h / 40 - 45 °C
13.1: lithium hydroxide hydrate / methanol; water / 24 h / 0 °C
13.2: Saturated solution
View Scheme
参考文献
Rodriguez, Ana R.; Spur, Bernd W.
Tetrahedron Letters, 2012 , vol. 53, # 32 p. 4169 - 4172