反应条件
1: 80 percent / Ti(Oi-Pr)4; (+)-diisopropyl tartrate; t-BuOOH / CH2Cl2 / -20 °C 2: 97 percent / 4-(dimethylamino)pyridine; triethylamine / CH2Cl2 / 16 h / 20 °C 3: 92 percent / 4,5-dichloro-3,6-dioxocyclohexa-1,4-diene-1,2-dicarbonitrile / CH2Cl2; H2O / 3 h / 20 °C 4: 100 percent / diisopropylethylamine / CH2Cl2 / 20 °C 5: 91 percent / NaN3 / dimethylformamide / 80 °C 6: 83 percent / triphenylphosphine / tetrahydrofuran; H2O / 20 °C 7: 90 percent / ethanol / 65 h / Heating 8: 82 percent / potassium bis(trimethylsilyl)amide / tetrahydrofuran / 2 h / -78 °C 9: 97 percent / potassium carbonate / acetonitrile / 5 h / Heating 10: 100 percent / tetra-n-butylammonium fluoride dihydrate / tetrahydrofuran / 14 h / 20 °C 11: (COCl)2; triethylamine / dimethylsulfoxide; CH2Cl2 / -78 - 20 °C 12: 71 percent / TiCl4 / CH2Cl2 / 15 h / -78 °C 13: OsO4; 4-methylmorpholine N-oxide / 2-methyl-propan-2-ol; tetrahydrofuran; H2O / 3 h / 20 °C 14: 45 mg / NaHCO3; NaIO4 / tetrahydrofuran; H2O / 3 h / 20 °C 15: 81 percent / hydrogen / 10 percent Pd/C / ethyl acetate / 24 h / 20 °C View Scheme
参考文献
Somfai, Peter; Marchand, Patrice; Torsell, Staffan; Lindstroem, Ulf M.
Tetrahedron, 2003 , vol. 59, # 8 p. 1293 - 1299
