2-[2-(2,2,2-三氟乙氧基)苯氧基]乙基溴合成路线 （共 3 条）
反应条件
potassium carbonate in water; N,N-dimethyl-formamide
反应条件
hydrogenchloride; sodium hydroxide
反应条件
1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 21.5 h / 110 °C / Sealed tube 2: hydrogen / 5 palladium on charcoal / ethanol / 19 h / 50 °C / 9000.9 Torr 3: sodium hydroxide; dihydrogen peroxide / dimethyl sulfoxide / 3.42 h / 0 - 20 °C / Inert atmosphere View Scheme
参考文献
ZENTIVA, K.S.; VLASAKOVA, Ruzena; HAJICEK, Josef; SLAVIKOVA, Marketa
Patent: WO2012/62229 A1, 2012 ;
