triethylamine in dichloromethane T=0°C; 0.25 h;

potassium carbonate in ethyl acetate; N,N-dimethyl-formamide

1: 3.8 g / K2CO3 / dimethylformamide / 18 h / 100 °C 2: Et3N / CH2Cl2 / 0.25 h / 0 °C View Scheme

1: 25.8 g / n-BuN4Br / 3.5 h / 180 °C 2: 3.8 g / K2CO3 / dimethylformamide / 18 h / 100 °C 3: Et3N / CH2Cl2 / 0.25 h / 0 °C View Scheme

1: potassium carbonate / N,N-dimethyl-formamide / 12 h / 100 °C / Sealed vessel 2: ethanethiol; AlCl3, aluminium chloride / dichloromethane / 4 h / 0 - 20 °C 3: potassium carbonate / acetonitrile / 66 h / 90 - 100 °C 4: triethylamine / dichloromethane / 1 h / 20 °C / Cooling with ice View Scheme

1: ethanethiol; AlCl3, aluminium chloride / dichloromethane / 4 h / 0 - 20 °C 2: potassium carbonate / acetonitrile / 66 h / 90 - 100 °C 3: triethylamine / dichloromethane / 1 h / 20 °C / Cooling with ice View Scheme

1: potassium carbonate / acetonitrile / 66 h / 90 - 100 °C 2: triethylamine / dichloromethane / 1 h / 20 °C / Cooling with ice View Scheme

1.1: sodium carbonate / acetonitrile / Reflux 1.2: 20 °C 2.1: potassium hydroxide; water / methanol / 20 °C View Scheme

1.1: potassium carbonate; potassium iodide / acetonitrile / 16 h / |Inert atmosphere; |Reflux 2.1: (S)-α-hydroxybenzeneacetic acid / methanol / 0.5 h / |Inert atmosphere; |Sonication 2.2: 1 h / 20 °C / |Inert atmosphere 3.1: triethylamine / dichloromethane / 16.5 h / 0 - 20 °C / |Inert atmosphere 4.1: potassium carbonate; water / ethanol / 6 h / |Inert atmosphere; |Reflux 5.1: sodium hydride / acetonitrile / 0.5 h / 0 °C / |Inert atmosphere 5.2: 16 h / 20 °C / |Inert atmosphere 6.1: palladium 10 on activated carbon; hydrogen / methanol / 1 h / 20 °C / |Inert atmosphere 7.1: trifluoroacetic acid / dichloromethane / 8 h / 0 - 20 °C / |Inert atmosphere View Scheme

1.1: sodium carbonate / acetonitrile / Reflux 1.2: 20 °C 2.1: potassium hydroxide; water / methanol / 20 °C 3.1: potassium hydroxide; dihydrogen peroxide / dimethyl sulfoxide / 20 °C View Scheme