9-甲氧基-1,5-二甲基-6H-吡啶并[4,3-b]咔唑合成路线 （共 5 条）
反应条件
1: 69 percent / SeO2 / dioxane / 5 h / Heating 2: 95 percent / CF3CO2H, NaBH3CN / ethanol / 0.5 h / Ambient temperature View Scheme
参考文献
Modi, Sandeep P.; McComb, Todd; Zayed, Abdel-Hadi; Oglesby, R. Christopher; Archer, Sydney
Tetrahedron, 1990 , vol. 46, # 16 p. 5555 - 5562
反应条件
1: 95 percent / oxychlorure de phosphore / toluene / 2 h / Heating
2: 93 percent / 30percent Pd/C / decahydronaphthalene / 2 h / Heating
View Scheme
参考文献
Jatztold-Howorko; Bisagni; Chermann
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 6 p. 541 - 544
反应条件
hydrogen bromide
1 h; Heating;
参考文献
Maftouh; Besselievre; Monsarrat; Lesca; Meunier; Husson; Paoletti
Journal of Medicinal Chemistry, 1985 , vol. 28, # 6 p. 708 - 714
反应条件
1: 70 percent / selenic anhydride / dioxane / 3 h / Heating
2: 2.) sodium borohydride / 1.) ethanol, reflux, 18 h, 2.) ethanol, room temperature, 30 min
View Scheme
参考文献
Jatztold-Howorko; Bisagni; Chermann
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 6 p. 541 - 544
反应条件
1: 70 percent / selenic anhydride / dioxane / 3 h / Heating
2: 2.) sodium borohydride / 1.) ethanol, reflux, 18 h, 2.) ethanol, room temperature, 30 min
View Scheme
参考文献
Jatztold-Howorko; Bisagni; Chermann
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 6 p. 541 - 544
