2,3-二氢-3-氧代-1H-吲唑-1-羧酸乙酯合成路线 (共 26 条)
反应条件
pyridine 2 h; Heating;
参考文献
Wyrick, Steven D.; Voorstad, P. Josee; Cocolas, George; Hall, Iris H.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 768 - 772
反应条件
1: 77 percent / toluene / 2 h / Heating 2: pyridine / 48 h / Ambient temperature View Scheme
参考文献
Anderson, Robert M.
Journal of Chemical Research, Miniprint, 1985 , # 12 p. 3933 - 3959
反应条件
1: pyridine / 48 h / Ambient temperature 2: 77 percent / toluene / 2 h / Heating 3: pyridine / 48 h / Ambient temperature View Scheme
参考文献
Anderson, Robert M.
Journal of Chemical Research, Miniprint, 1985 , # 12 p. 3933 - 3959
参考文献
Heller; Jacobsohn
Chemische Berichte, 1921 , vol. 54, p. 1115
Full Text Show Details
Pieroni; Giannini
Gazzetta Chimica Italiana, 1924 , vol. 54, p. 176
反应条件
pyridine 48 h; Ambient temperature;
参考文献
Anderson, Robert M.
Journal of Chemical Research, Miniprint, 1985 , # 12 p. 3933 - 3959
参考文献
Pieroni; Giannini
Gazzetta Chimica Italiana, 1924 , vol. 54, p. 176
反应条件
in acetone 24 h; RefluxAlkaline conditions;
参考文献
Vega, Maria Celeste; Rolon, Miriam; Montero-Torres, Alina; Fonseca-Berzal, Cristina; Escario, Jose Antonio; Gomez-Barrio, Alicia; Galvez, Jorge; Marrero-Ponce, Yovani; Aran, Vicente J.
European Journal of Medicinal Chemistry, 2012 , vol. 58, p. 214 - 227
反应条件
1: With caesium carbonate in acetone 24 h; Reflux; 2: With potassium hydroxide in ethanol T=20°C; 1 h; 3: With hydrogenchloride in water
参考文献
Vega, Maria Celeste; Rolon, Miriam; Montero-Torres, Alina; Fonseca-Berzal, Cristina; Escario, Jose Antonio; Gomez-Barrio, Alicia; Galvez, Jorge; Marrero-Ponce, Yovani; Aran, Vicente J.
European Journal of Medicinal Chemistry, 2012 , vol. 58, p. 214 - 227
反应条件
1: 1.) KOH / 1.) C2H5OH, 2.) C2H5OH, reflux, 6 h 2: 66 percent / KOH / ethanol / 4 h / Heating View Scheme
参考文献
Wyrick, Steven D.; Voorstad, P. Josee; Cocolas, George; Hall, Iris H.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 768 - 772
反应条件
1: in acetone 24 h; Alkaline conditionsReflux; 2: With potassium hydroxide in ethanol T=20°C; 1 h;
参考文献
Vega, Maria Celeste; Rolon, Miriam; Montero-Torres, Alina; Fonseca-Berzal, Cristina; Escario, Jose Antonio; Gomez-Barrio, Alicia; Galvez, Jorge; Marrero-Ponce, Yovani; Aran, Vicente J.
European Journal of Medicinal Chemistry, 2012 , vol. 58, p. 214 - 227