2,3-二氢-3-氧代-1H-吲唑-1-羧酸乙酯合成路线 （共 26 条）
反应条件
1: in acetone 24 h; Alkaline conditionsReflux; 2: With potassium hydroxide in ethanol T=20°C; 1 h;
参考文献
Vega, Maria Celeste; Rolon, Miriam; Montero-Torres, Alina; Fonseca-Berzal, Cristina; Escario, Jose Antonio; Gomez-Barrio, Alicia; Galvez, Jorge; Marrero-Ponce, Yovani; Aran, Vicente J.
European Journal of Medicinal Chemistry, 2012 , vol. 58, p. 214 - 227
反应条件
potassium hydroxide
1.) C2H5OH, 2.) C2H5OH, reflux, 6 h; Yield given. Multistep reaction;
参考文献
Wyrick, Steven D.; Voorstad, P. Josee; Cocolas, George; Hall, Iris H.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 768 - 772
反应条件
potassium hydroxide
1.) C2H5OH, 2.) C2H5OH, reflux, 6 h; Yield given. Multistep reaction;
参考文献
Wyrick, Steven D.; Voorstad, P. Josee; Cocolas, George; Hall, Iris H.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 768 - 772
反应条件
potassium hydroxide
1.) C2H5OH, 2.) C2H5OH, reflux, 6 h; Yield given. Multistep reaction;
参考文献
Wyrick, Steven D.; Voorstad, P. Josee; Cocolas, George; Hall, Iris H.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 768 - 772
反应条件
potassium hydroxide
1.) C2H5OH, 2.) C2H5OH, reflux, 6 h; Yield given. Multistep reaction;
参考文献
Wyrick, Steven D.; Voorstad, P. Josee; Cocolas, George; Hall, Iris H.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 768 - 772
反应条件
1: 1.) KOH / 1.) C2H5OH, 2.) C2H5OH, reflux, 6 h
2: 98 percent / KOH / ethanol / 4 h / Heating
View Scheme
参考文献
Wyrick, Steven D.; Voorstad, P. Josee; Cocolas, George; Hall, Iris H.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 768 - 772
反应条件
1: 1.) KOH / 1.) C2H5OH, 2.) C2H5OH, reflux, 6 h
2: 93 percent / KOH / ethanol / 4 h / Heating
View Scheme
参考文献
Wyrick, Steven D.; Voorstad, P. Josee; Cocolas, George; Hall, Iris H.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 768 - 772
反应条件
1: 1.) KOH / 1.) C2H5OH, 2.) C2H5OH, reflux, 6 h
2: 100 percent / KOH / ethanol / 4 h / Heating
View Scheme
参考文献
Wyrick, Steven D.; Voorstad, P. Josee; Cocolas, George; Hall, Iris H.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 768 - 772
反应条件
1: 1.) KOH / 1.) C2H5OH, 2.) C2H5OH, reflux, 6 h
2: 81 percent / KOH / ethanol / 4 h / Heating
View Scheme
参考文献
Wyrick, Steven D.; Voorstad, P. Josee; Cocolas, George; Hall, Iris H.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 768 - 772
反应条件
1: 1.) KOH / 1.) C2H5OH, 2.) C2H5OH, reflux, 6 h
2: 50 percent / KOH / ethanol / 4 h / Heating
View Scheme
参考文献
Wyrick, Steven D.; Voorstad, P. Josee; Cocolas, George; Hall, Iris H.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 768 - 772
