2,3-二氢-3-氧代-1H-吲唑-1-羧酸乙酯合成路线 （共 26 条）
反应条件
1: 1.) KOH / 1.) C2H5OH, 2.) C2H5OH, reflux, 6 h
2: 69 percent / KOH / ethanol / 4 h / Heating
View Scheme
参考文献
Wyrick, Steven D.; Voorstad, P. Josee; Cocolas, George; Hall, Iris H.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 768 - 772
反应条件
1: 1.) KOH / 1.) C2H5OH, 2.) C2H5OH, reflux, 6 h
2: 63 percent / KOH / ethanol / 4 h / Heating
View Scheme
参考文献
Wyrick, Steven D.; Voorstad, P. Josee; Cocolas, George; Hall, Iris H.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 768 - 772
反应条件
1: 1.) KOH / 1.) C2H5OH, 2.) C2H5OH, reflux, 6 h
2: 75 percent / KOH / ethanol / 4 h / Heating
View Scheme
参考文献
Wyrick, Steven D.; Voorstad, P. Josee; Cocolas, George; Hall, Iris H.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 768 - 772
反应条件
1: 1.) KOH / 1.) C2H5OH, 2.) C2H5OH, reflux, 6 h
2: 40 percent / KOH / ethanol / 4 h / Heating
View Scheme
参考文献
Wyrick, Steven D.; Voorstad, P. Josee; Cocolas, George; Hall, Iris H.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 768 - 772
反应条件
1: 60 percent / EtONa / ethyl acetate / 1.5 h / Heating
2: KOH / ethanol / 4 h / Heating
View Scheme
参考文献
Wyrick, Steven D.; Voorstad, P. Josee; Cocolas, George; Hall, Iris H.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 768 - 772
反应条件
1: 1.) KOH / 1.) C2H5OH, 2.) C2H5OH, reflux, 6 h
2: 72 percent / CrO3, aq. CH3COOH / Ambient temperature
View Scheme
参考文献
Wyrick, Steven D.; Voorstad, P. Josee; Cocolas, George; Hall, Iris H.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 768 - 772
