1-(2-羟基-4,6-二甲基苯基)乙酮合成路线 （共 33 条）
反应条件
sodium hydroxide T=50°C;
参考文献
Al-Ka'bi, Ja'far; Gore, Peter H.; Moonga, Baljit; Al-Shiebani, Ikbal S.; Shibaldain, Nazar L.; et al.
Journal of Chemical Research, Miniprint, 1986 , # 7 p. 2201 - 2226
反应条件
1: LiH / tetrahydrofuran 2: concentrated HCl; AcOH / Heating View Scheme
参考文献
Bayer, V.; Pastor, R. E.; Cambon, A. R.
Journal of Fluorine Chemistry, 1982 , vol. 20, p. 497 - 506
反应条件
1: 3,5-dimethyl-phenol With titanium tetrachloride
T=20°C;
2: acetyl chloride T=20 - 120°C; 1.25 h;
参考文献
Zaveri, Nurulain; Chao, Wan-Ru; Bensari, Ahlem
Patent: US2004/110790 A1, 2004 ;
Location in patent: Page 17 ;
反应条件
aluminium trichloride
10 h; Heating;
参考文献
Goud, B. Satish; Panneerselvam, Kaliyamoorthy; Zacharias, David E.; Desiraju, Gautam R.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1995 , # 2 p. 325 - 330
反应条件
potassium carbonate in dimethyl sulfoxide
T=110 - 120°C; 16 h;
参考文献
Krasavtsev I. I.; Basalkevich E. D.; Lozinskii M. O.
Journal of Organic Chemistry USSR (English Translation), 1985 , vol. 21, p. 1632 - 1634
Zhurnal Organicheskoi Khimii, 1985 , vol. 21, # 8 p. 1787 - 1790
反应条件
hydrogen; palladium on activated charcoal in ethanol
P=26600 Torr; 4 h; Ambient temperature;
参考文献
Benincori, Tiziana; Sannicolo, Franco
Journal of Organic Chemistry, 1988 , vol. 53, # 6 p. 1309 - 1312
反应条件
titanium tetrachloride in dichloromethane
T=-78 - 20°C; 20 h;
参考文献
Ullah, Ehsan; Appel, Bettina; Fischer, Christine; Langer, Peter
Tetrahedron, 2006 , vol. 62, # 41 p. 9694 - 9700
反应条件
bis(acetylacetonato) palladium; triphenylphosphine in acetylacetone
T=140°C; 24 h;
参考文献
Moreno-Manas, M.; Trius, A.
Tetrahedron, 1981 , vol. 37, # 17 p. 3009 - 3016
反应条件
1: 0.65 percent / PPA / 0.25 h / 80 °C
2: 0.3 g / H2 / Pd/C 10percent / ethanol / 4 h / 26600 Torr / Ambient temperature
View Scheme
参考文献
Benincori, Tiziana; Sannicolo, Franco
Journal of Organic Chemistry, 1988 , vol. 53, # 6 p. 1309 - 1312
反应条件
1: 1.) sodium ethoxide / 1.) EtOH, 2.) acetonitrile, 25 deg C, 15 min
2: 0.65 percent / PPA / 0.25 h / 80 °C
3: 0.3 g / H2 / Pd/C 10percent / ethanol / 4 h / 26600 Torr / Ambient temperature
View Scheme
参考文献
Benincori, Tiziana; Sannicolo, Franco
Journal of Organic Chemistry, 1988 , vol. 53, # 6 p. 1309 - 1312
