2,6-二甲基-4H-苯并吡喃-4-酮合成路线 （共 30 条）
反应条件
hydrazine hydrate in ethanol 0.25 h; Heating;
参考文献
Hamed, Ashraf A.; Madkour, Hassan M. F.; Nuaimi, Ibrahim S. Al.; Hussain, Badria A.
Anales de Quimica, 1994 , vol. 90, # 5-6 p. 359 - 364
反应条件
1: 85 percent / Na / diethyl ether / Heating 2: 10percent aq. KOH / 4 h / Heating View Scheme
参考文献
Wittig
Chemische Berichte, 1924 , vol. 57, p. 92
Justus Liebigs Annalen der Chemie, 1926 , vol. 446, p. 157 Anm. 2, 177
参考文献
Wittig
Chemische Berichte, 1924 , vol. 57, p. 92
Justus Liebigs Annalen der Chemie, 1926 , vol. 446, p. 157 Anm. 2, 177
反应条件
Jone's reagent in acetone
T=0°C; 0.0833333 h;
参考文献
Fan, Xuesen; Wang, Yangyang; Qu, Yingying; Xu, Haiyun; He, Yan; Zhang, Xinying; Wang, Jianji
Journal of Organic Chemistry, 2011 , vol. 76, # 3 p. 982 - 985
反应条件
hydrogenchloride in methanol
T=20°C; 14 h; Inert atmosphere;
参考文献
Zhao, Dongbing; Beiring, Bernhard; Glorius, Frank
Angewandte Chemie - International Edition, 2013 , vol. 52, # 32 p. 8454 - 8458
Angew. Chem., 2013 , vol. 125, # 32 p. 8612 - 8616,5
反应条件
aluminum oxide in dichloromethane
T=20°C; Decarboxylation; 16 h;
参考文献
Ghosh, Chandra Kanta; Bhattacharyya, Samita
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1999 , vol. 38, # 2 p. 166 - 172
反应条件
1: p-toluenesulfonic acid
2: 15 percent / benzene / Irradiation
View Scheme
参考文献
Garcia, Hermenegildo; Martinez-Utrilla, Roberto; Miranda, Miguel Angel
Tetrahedron Letters, 1981 , vol. 22, # 18 p. 1749 - 1750
反应条件
1: 81 percent / 4-(N,N-dimethylamino)pyridine, N,N'-dicyclohexylcarbodiimide / CHCl3 / 0.25 h / Ambient temperature
2: 53 percent / hexane / 6 h / Ambient temperature; Irradiation
3: 4-toluenesulphonic acid / CH2Cl2 / 0.5 h / Heating
View Scheme
参考文献
Alvaro, Mercedes; Garcia, Hermenegildo; Iborra, Sara; Miranda, Miguel A.; Primo, Jaime
Tetrahedron, 1987 , vol. 43, # 1 p. 143 - 148
反应条件
1: zinc / tetrahydrofuran; N,N-dimethyl-formamide / 20 °C
2: Jone's reagent / acetone / 0.08 h / 0 °C
View Scheme
参考文献
Fan, Xuesen; Wang, Yangyang; Qu, Yingying; Xu, Haiyun; He, Yan; Zhang, Xinying; Wang, Jianji
Journal of Organic Chemistry, 2011 , vol. 76, # 3 p. 982 - 985
反应条件
1: sodium hydride / tetrahydrofuran; mineral oil / |Inert atmosphere; |Reflux
2: hydrogenchloride / methanol / 14 h / 20 °C / |Inert atmosphere
View Scheme
参考文献
Zhao, Dongbing; Beiring, Bernhard; Glorius, Frank
Angewandte Chemie - International Edition, 2013 , vol. 52, # 32 p. 8454 - 8458
Angew. Chem., 2013 , vol. 125, # 32 p. 8612 - 8616,5
