3,5-二-叔-丁基-4-羟基苯乙腈合成路线 (共 12 条)
反应条件
hydrogenchloride; aluminum tri-bromide in diethyl ether
a) 20 deg C, 12 h, b) 100 deg C, 2 h;
参考文献
Kelarev, V. I.; Koshelev, V. N.; Belov, N. V.; Malova, O. V.; Karakhanov, R. A.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1994 , vol. 30, # 2 p. 218 - 221
Khimiya Geterotsiklicheskikh Soedinenii, 1994 , # 2 p. 240 - 243
反应条件
lithium aluminium tetrahydride in diethyl ether
T=0°C; 4 h; RefluxInert atmosphere;
参考文献
Devine, Shane M.; Gregg, Alison; Figler, Heidi; McIntosh, Kate; Urmaliya, Vijay; Linden, Joel; Pouton, Colin W.; White, Paul J.; Bottle, Steven E.; Scammells, Peter J.
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 9 p. 3078 - 3087