1-异氰酰基-3-甲基丁烷合成路线 （共 14 条）
反应条件
1: With carbonyl diimidazole in acetonitrile T=20°C; Lossen rearrangement; 0.5 h; Inert atmosphere; 2: in acetonitrile T=60°C; Lossen rearrangement; Inert atmosphere;
参考文献
Organic Letters, , vol. 11, # 24 p. 5622 - 5625
反应条件
1: BF3-Et2O / toluene 2: H2 / Raney-Ni / ethanol / 55 - 76 °C 3: bis-(4-isocyanato-phenyl)-methane, PhNH2, HCHO, COCl2 / 220 - 240 °C View Scheme
参考文献
Chemische Berichte, , vol. 98, p. 1097 - 1110
反应条件
sodium azide in benzene 36 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 29, # 6 p. 972 - 978
反应条件
1: H2 / Raney-Ni / ethanol / 55 - 76 °C 2: bis-(4-isocyanato-phenyl)-methane, PhNH2, HCHO, COCl2 / 220 - 240 °C View Scheme
参考文献
Chemische Berichte, , vol. 98, p. 1097 - 1110
反应条件
1: H2 / Raney-Ni / ethanol / 55 - 76 °C 2: bis-(4-isocyanato-phenyl)-methane, PhNH2, HCHO, COCl2 / 220 - 240 °C View Scheme
参考文献
Chemische Berichte, , vol. 98, p. 1097 - 1110
反应条件
carbon in ethyl acetate 5 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 42, # 4 p. 593 - 600
反应条件
1: 3-methyl-1-butamine; 1,1,1,3,3,3-hexamethyl-disilazane With sulfuric acid 2 h; Heating; 2: phosgene in toluene T=0°C; 3: T=140°C; 4 h; Further stages.;
参考文献
Russian Journal of General Chemistry, , vol. 76, # 3 p. 469 - 477
反应条件
phosphorus pentoxide
参考文献
Chemische Berichte, , vol. 12, p. 1333
反应条件
1: 3-methyl-1-butamine; 1,1,1,3,3,3-hexamethyl-disilazane With sulfuric acid 2 h; Heating; 2: phosgene in toluene T=0°C; Further stages. Title compound not separated from byproducts.;
参考文献
Russian Journal of General Chemistry, , vol. 76, # 3 p. 469 - 477
反应条件
1: diethyl ether 2: P2O5 View Scheme
参考文献
Chemische Berichte, , vol. 12, p. 1333
