1: 72 percent / NaOEt / 24 h / Ambient temperature 2: 77 percent / methanol / 4 h / Heating View Scheme

sodium ethanolate 24 h; Ambient temperature;

1: 72 percent / NaOEt / 24 h / Ambient temperature 2: 77 percent / methanol / 4 h / Heating 3: 78 percent / pyridine / 2 h View Scheme

<b>Multi-step reaction with 5 steps<br /> </b>1: DMAP / acetonitrile / 2 h / Ambient temperature<br />2: 72 percent / AIBN, Bu₃SnH / toluene / 6 h / 80 &deg;C<br />3: HCOOH / 2 h / 50 &deg;C<br />4: pyridine / 2 h / Ambient temperature<br />5: 1.) hexamethyldisilazane, (NH₄)2SO₄, 2.) trimethylsilyl triflate / 1.) reflux, 1,2-dichloroethane, RT, 1.5 h<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: HCOOH / 2 h / 50 &deg;C<br />2: pyridine / 2 h / Ambient temperature<br />3: 1.) hexamethyldisilazane, (NH₄)2SO₄, 2.) trimethylsilyl triflate / 1.) reflux, 1,2-dichloroethane, RT, 1.5 h<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11338472', constants.ctx, '0')">ammonium sulfate</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1868911', constants.ctx, '0')">trimethylsilyl trifluoromethanesulfonate</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '635752', constants.ctx, '0')">1,1,1,3,3,3-hexamethyl-disilazane</a> <br />&nbsp;1.) reflux, 1,2-dichloroethane, RT, 1.5 h;&nbsp;&nbsp;Yield given. Multistep reaction;&nbsp;<br /> &nbsp;