Rhodococcus ruber alcohol dehydrogenase; nicotinamide adenine dinucleotide; isopropyl alcohol; magnesium chloride in aq. phosphate buffer T=30°C; pH=7; 48 h; Inert atmosphereSchlenk techniqueEnzymatic reaction; Catalytic behavior; Reagent/catalystTime; enantioselective reaction;

1: With (S)-2-methyl-quinazolinap rhodium; benzo[1,3,2]dioxaborole in tetrahydrofuran T=0°C; 2 h; 2: With sodium hydroxide; dihydrogen peroxide in tetrahydrofuran; ethanol T=0 - 20°C;

1: With (R)-2-tert-butyl-quinazolinap rhodium; benzo[1,3,2]dioxaborole in tetrahydrofuran T=20°C; 2 h; 2: With sodium hydroxide; dihydrogen peroxide in tetrahydrofuran; ethanol T=0 - 20°C; Title compound not separated from byproducts;

lithium aluminium tetrahydride in tetrahydrofuran T=20°C; 5 h;