2-甲基-1,2,3,4-四氢异喹啉合成路线 （共 65 条）
反应条件
AFA in dichloromethane
T=0 - 21°C;
参考文献
Tokitoh, Norihiro; Okazaki, Renji
Chemistry Letters, 1985 , p. 1517 - 1520
反应条件
L-Selectridereg; in tetrahydrofuran
T=20°C; 72 h;
参考文献
Coop, Andrew; Rice, Kenner C.
Tetrahedron Letters, 1998 , vol. 39, # 49 p. 8933 - 8934
反应条件
potassium hydride; triethylamine in ethylene glycol dimethyl ether
T=0 - 20°C;
参考文献
Graulich; Mercier; Scuvee-Moreau; Seutin; Liegeois
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 4 p. 1201 - 1209
反应条件
1: With naphthalene; lithium in tetrahydrofuran
T=-30°C; 2 h;
2: With water in tetrahydrofuran
T=-30°C; 0.5 h;
参考文献
Azzena, Ugo; Pisano, Luisa; Pittalis, Mario
Heterocycles, 2004 , vol. 63, # 2 p. 401 - 409
反应条件
1: NaOH / toluene; H2O / 12 h / 20 °C
2: 2.48 g / LiAlH4 / tetrahydrofuran / 36 h / Heating
View Scheme
参考文献
Lemoucheux, Laurent; Rouden, Jacques; Ibazizene, Meziane; Sobrio, Franck; Lasne, Marie-Claire
Journal of Organic Chemistry, 2003 , vol. 68, # 19 p. 7289 - 7297
反应条件
n-butyllithium; diisopropylamine; iPr-BOX in hexane; toluene
T=-78 - -20°C; 1 h; Inert atmosphere; enantioselective reaction;
参考文献
Ogata, Tokutaro; Kimachi, Tetsutaro; Yamada, Ken-Ichi; Yamamoto, Yasutomo; Tomioka, Kiyoshi
Heterocycles, 2012 , vol. 86, # 1 p. 469 - 485
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
36 h; Heating;
参考文献
Lemoucheux, Laurent; Rouden, Jacques; Ibazizene, Meziane; Sobrio, Franck; Lasne, Marie-Claire
Journal of Organic Chemistry, 2003 , vol. 68, # 19 p. 7289 - 7297
反应条件
methyl (triphenylphosphoranylidene)acetate in dichloromethane
120 h; Ambient temperature;
参考文献
Desmaele, Didier
Tetrahedron Letters, 1996 , vol. 37, # 8 p. 1233 - 1236
反应条件
in methanol; dichloromethane
120 h; Ambient temperature;
参考文献
Desmaele, Didier
Tetrahedron Letters, 1996 , vol. 37, # 8 p. 1233 - 1236
反应条件
benzenethiol sodium salt in acetonitrile; butanone
Heating;
参考文献
Manoharan, T. Samuel; Madyastha, K. Madhava; Singh, B. B.; Bhatnagar, S. P.; Weiss, Ulrich
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 1 p. 5 - 11
