N-Boc-吡咯-2-甲醛合成路线 （共 5 条）
反应条件
N,N-dimethoxy-4-amino-pyridine; triethylamine in dichloromethane T=20°C; 0.5 h;
参考文献
KABUSHIKI KAISHA YAKULT HONSHA
Patent: EP1864972 A1, 2007 ;
Location in patent: Page/Page column 20 ;
反应条件
4-(N,N-dimethlyamino)pyridine in tetrahydrofuran; dichloromethane; water
参考文献
Merck, Sharp and Dohme Ltd.
Patent: US5567726 A1, 1996 ;
反应条件
sodium hydride 1.) THF, RT, 15 min, 2.) THF, RT, 60 min; Multistep reaction;
参考文献
Journal of the American Chemical Society, , vol. 120, # 8 p. 1741 - 1746
反应条件
in 2,2,2-trifluoroethanol T=100°C; 0.5 h; microwave irradiation;
参考文献
Synthetic Communications, , vol. 38, # 21 p. 3840 - 3853
反应条件
1: 64 percent / sodium acetate; methylamine hydrochloride / methanol / 21 h / 20 °C
2: 52 percent / NaBH4 / methanol; dimethylformamide / 0.25 h
View Scheme
参考文献
Kim, Han-Je; Dogutan, Dilek Kiper; Ptaszek, Marcin; Lindsey, Jonathan S.
Tetrahedron, 2007 , vol. 63, # 1 p. 37 - 55
