1.1: TBAF / tetrahydrofuran / 0.33 h 2.1: NaOH / dioxane; H2O / 0.17 h 2.2: 40.3 percent / dioxane; H2O / 20 h View Scheme

tetrabutyl ammonium fluoride in tetrahydrofuran 0.333333 h;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '605268', constants.ctx, '0')">diethylamine</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '741857', constants.ctx, '0')">acetonitrile</a> <br />1&nbsp;h;&nbsp;<br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '508906', constants.ctx, '0')">1,8-diazabicyclo[5.4.0]undec-7-ene</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '741857', constants.ctx, '0')">acetonitrile</a> <br />18&nbsp;h;&nbsp;&nbsp;Ambient temperature;&nbsp;<br /> &nbsp;