1: 2 M NaOH / Ambient temperature; lipase Pseudomonas cepacia, pH=7.2 2: 60 percent / 4-N,N-dimethylaminopyridine / CH2Cl2 / 48 h / Ambient temperature 3: 90 percent / LiAlH4 / diethyl ether / 1 h / Ambient temperature View Scheme

lipase from Pseudomonas Cepacia; sodium chloride; calcium chloride; sodium hydroxide; BSA in water T=37°C; pH=7.5; Enzymatic reaction; optical yield given as percent ee;