1-苄基-4-(4-硝基苯基)哌嗪合成路线 (共 10 条)
反应条件
potassium carbonate in dimethyl sulfoxide T=100°C; 63 h;
参考文献
Lauteslager, Xavier Y.; Van Stokkum, Ivo H. M.; Van John Ramesdonk; Bebelaar, Dick; Fraanje, Jan; Goubitz, Kees; Schenk, Henk; Brouwer, Albert M.; Verhoeven, Jan W.
European Journal of Organic Chemistry, 2001 , # 16 p. 3105 - 3118
反应条件
potassium acetate; 1-n-butyl-3-methylimidazolium tetrafluoroborate 0.025 h; microwave irradiation;
参考文献
Angrish, Chetna; Kumar, Anil; Chauhan
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005 , vol. 44, # 7 p. 1515 - 1518
反应条件
triethylamine in acetonitrile 12 h; Reflux;
参考文献
F2G LTD
Patent: WO2009/130481 A1, 2009 ;
Location in patent: Page/Page column 136-137 ;
反应条件
potassium carbonate in butanone T=80°C; 24 h;
参考文献
Sukalovic, Vladimir; Zlatovic, Mario; Andric, Deana; Roglic, Goran; Kostic-Rajacic, Sladjana; Soskic, Vukic
Arzneimittel-Forschung/Drug Research, 2005 , vol. 55, # 3 p. 145 - 152
参考文献
A. H. Robins Company, Incorporated
Patent: US5086055 A1, 1992 ;
参考文献
WO2007/71752 A2, ;
Page/Page column 79 ;
WO 2007/071752 A2
反应条件
in acetonitrile 12 h; Heating;
参考文献
Kotsuki; Kobayashi; Suenaga; Nishizawa
Synthesis, 1990 , # 12 p. 1145 - 1147
反应条件
1: NEt3 / CH2Cl2 / 0.17 h / -15 °C 2: 87 percent / acetonitrile / 12 h / Heating View Scheme
参考文献
Synthesis, , # 12 p. 1145 - 1147
反应条件
sodium tetrahydroborate; nickel dichloride in methanol T=20°C; 1 h;
参考文献
Lauteslager, Xavier Y.; Van Stokkum, Ivo H. M.; Van John Ramesdonk; Bebelaar, Dick; Fraanje, Jan; Goubitz, Kees; Schenk, Henk; Brouwer, Albert M.; Verhoeven, Jan W.
European Journal of Organic Chemistry, 2001 , # 16 p. 3105 - 3118
参考文献
University of Tennessee Research Foundation
Patent: US2005/222408 A1, 2005 ;