1-(2-碘乙基)-2-甲基-5-硝基-1H-咪唑合成路线 (共 4 条)
反应条件
sodium iodide in acetone T=90°C; 12 h;
参考文献
Li, Huan-Qiu; Xiao, Zhu-Ping; Fang, Rui-Qin; Zhu, Hai-Liang
Journal of Chemical Crystallography, 2008 , vol. 38, # 6 p. 461 - 466
反应条件
sodium iodide in acetone 4 h; Heating;
参考文献
Hay, Michael P.; Lee, Ho H.; Wilson, William R.; Roberts, Peter B.; Denny, William A.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 11 p. 1928 - 1941
反应条件
1H-imidazole; iodine; triphenylphosphine in dichloromethane T=20°C; Mitsunobu reaction;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 1 p. 394 - 397
反应条件
1: 62 percent / NaBr / dimethylformamide / 4 h / 100 °C 2: 45 percent / NaI / acetone / 4 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 11 p. 1928 - 1941