1-CBZ-4-哌啶甲酰肼合成路线 （共 2 条）
反应条件
hydrazine hydrate in ethanol Inert atmosphere of ArReflux;
参考文献
OSLO UNIVERSITY HOSPITAL HF; HOLSWORTH, Dan; WAALER, Jo; MACHON, Ondrej; KRAUSS, Stefan; GOLDING, Louise
Patent: WO2010/139966 A1, 2010 ;
Location in patent: Page/Page column 117; 119 ;
反应条件
1: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 15 h / 20 °C 2: trifluoroacetic acid / dichloromethane / 1 h / 20 °C View Scheme
参考文献
EIGER BIOPHARMACEUTICALS, INC.; YANG, Wenjin; CHOONG, Ingrid
Patent: WO2011/49987 A2, 2011 ;
WO 2011/049987 A2
