4-(2-氟-3-吡啶基)-4-羟基-1-哌啶羧酸苯甲酯合成路线 （共 1 条）
反应条件
1: 2-fluoro-pyridine With 2,2,6,6-tetramethyl-piperidine; n-butyllithium in tetrahydrofuran; hexane T=-78 - -70°C; 1.25 h; Inert atmosphere; 2: 1-benzyloxycarbonyl-piperidin-4-one in tetrahydrofuran; hexane T=-70°C; 1 h; Inert atmosphere;
参考文献
Moseley, Jonathan D.; Moss, William O.; Welham, Matthew J.
Organic Process Research and Development, 2001 , vol. 5, # 5 p. 491 - 497
