苄基4-羟基-4-(2-吡啶基)-1-哌啶羧酸酯合成路线 （共 3 条）
反应条件
n-butyllithium; NH4Cl in tetrahydrofuran
参考文献
Stewart, Andrew O.; Kolasa, Teodozyj
Patent: US2003/232836 A1, 2003 ;
Location in patent: Page 49 ;
US 20030232836 A1
反应条件
1: 2-bromo-pyridine With n-butyllithium in tetrahydrofuran; hexanes T=-60°C; 0.5 h; 2: 1-benzyloxycarbonyl-piperidin-4-one in tetrahydrofuran; hexanes T=-60°C; 0.25 h;
参考文献
Bhatia, Pramila A.; Daanen, Jerome F.; Hakeem, Ahmed A.; Kolasa, Teodozyj; Matulenko, Mark A.; Mortell, Kathleen H.; Patel, Meena V.; Stewart, Andrew O.; Wang, Xueqing; Xia, Zhiren; Zhang, Henry Q.
Patent: US2003/229094 A1, 2003 ;
Location in patent: Page 73 ;
US 20030229094 A1
参考文献
Zeneca Limited
Patent: US5654299 A1, 1997 ;
