2,2,6,6-tetramethyl-piperidine-N-oxyl; oxygen; tri-n-butyl-tin hydride in benzene T=70°C; 1 h;

1: 83 percent / Bu3SnH / benzene / 1 h / 70 °C 2: 90 percent / Zn, aq. CH3COOH / tetrahydrofuran / 2 h / 70 °C View Scheme

manganese; NiBr2bipy; trifluoroacetic acid in N,N-dimethyl-formamide T=50°C; Heck Reaction; Inert atmosphere; Overall yield = 60percent; Overall yield = 139 mg;