(1S,3R)-N-BOC-1-氨基环戊烷-3-羧酸合成路线 （共 6 条）
反应条件
palladium 10 on activated carbon; hydrogen in ethanol 12 h;
参考文献
Rodriguez-Vazquez, Nuria; Salzinger, Stephan; Silva, Luis F.; Amorin, Manuel; Granja, Juan R.
European Journal of Organic Chemistry, 2013 , # 17 p. 3477 - 3493
反应条件
1: 99 percent / H2 / Pd/C / ethyl acetate 2: 93 percent / aq. HCl / 48 h / 20 °C 3: DIEA / H2O; dioxane / 3 h / 20 °C View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 44, # 35 p. 5710 - 5713
反应条件
Product distribution / selectivity;
参考文献
WO2005/75426 A1, ;
Page/Page column 30 ;
WO 2005/075426 A1
反应条件
N-ethyl-N,N-diisopropylamine in 1,4-dioxane; water T=20°C; 3 h;
参考文献
Angewandte Chemie - International Edition, , vol. 44, # 35 p. 5710 - 5713
反应条件
1: 93 percent / aq. HCl / 48 h / 20 °C 2: DIEA / H2O; dioxane / 3 h / 20 °C View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 44, # 35 p. 5710 - 5713
反应条件
1.1: N-ethyl-N,N-diisopropylamine / water; 1,4-dioxane / 3 h / 20 °C 1.2: pH 3 / |Acidic conditions 2.1: (R)-1-phenyl-ethyl-amine / hexane; chloroform / |Resolution of racemate 3.1: palladium 10 on activated carbon; hydrogen / ethanol / 12 h View Scheme
参考文献
European Journal of Organic Chemistry, , # 17 p. 3477 - 3493
