4-乙酰基-1H-吡咯-2-羧酸合成路线 （共 7 条）
反应条件
sodium hydroxide 1 h; Heating;
参考文献
Garrido, Daniel O. A.; Buldain, Graciela; Ojea, Maria I.; Frydman, Benjamin
Journal of Organic Chemistry, 1988 , vol. 53, # 2 p. 403 - 407
反应条件
1: 96.7 percent / AlCl3 / 1,2-dichloro-ethane / 1.25 h / Ambient temperature 2: 96.7 percent / ethanol / 3.2 h / 0 °C 3: 15percent aq. KOH / 1 h / 55 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 44, # 1 p. 48 - 54
反应条件
1: 88.9 percent / AlCl3 / 1,2-dichloro-ethane / 1 h / Ambient temperature 2: 15percent aq. KOH / 1 h / 55 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 44, # 1 p. 48 - 54
反应条件
water; potassium carbonate T=20°C; 2 h;
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 18 p. 6306 - 6311
反应条件
potassium hydroxide T=55°C; 1 h;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 44, # 1 p. 48 - 54
反应条件
copper (II) chromite in quinoline T=200°C; 0.2 h;
参考文献
Anderson, Hugh J.; Clase, J. Andrew; Loader, Charles E.
Synthetic Communications, 1987 , vol. 17, # 4 p. 401 - 408
反应条件
dowtherm A T=194 - 208°C; 6.3 h; Yield given;
参考文献
Tani; Ariyasu; Nishiyama; Hagiwara; Watanabe; Yokoyama; Murakami
Chemical and Pharmaceutical Bulletin, 1996 , vol. 44, # 1 p. 48 - 54
