5-苯基-1H-吡咯-3-羧酸乙酯合成路线 （共 15 条）
反应条件
silver tetrafluoroborate; PPh3 gold(I) chloro complex in toluene
T=100°C; 18 h; Microwave irradiation; Overall yield = 43 percent; Overall yield = 31 mg; regioselective reaction;
参考文献
Ngwerume, Simbarashe; Lewis, William; Camp, Jason E.
Journal of Organic Chemistry, 2013 , vol. 78, # 3 p. 920 - 934
反应条件
1: 5 percent / NEt3 / CH2Cl2 / 6 h / Heating
2: acetone / 3 h / 20 °C / UV-irradiation
View Scheme
参考文献
Cox, Matthew; Heidarizadeh, Fariba; Pragei, Rolf H.
Australian Journal of Chemistry, 2000 , vol. 53, # 8 p. 665 - 671
反应条件
1: 5 percent / NEt3 / CH2Cl2 / 6 h / Heating
2: acetone / 3 h / 20 °C / UV-irradiation
View Scheme
参考文献
Cox, Matthew; Heidarizadeh, Fariba; Pragei, Rolf H.
Australian Journal of Chemistry, 2000 , vol. 53, # 8 p. 665 - 671
反应条件
1: pyridine; hydroxylamine hydrochloride / ethanol / 12 h / |Reflux
2: PPh3 gold(I) chloro complex; silver trifluoromethanesulfonate / toluene / 12 h / 100 °C / |Microwave irradiation
View Scheme
参考文献
Ngwerume, Simbarashe; Lewis, William; Camp, Jason E.
Journal of Organic Chemistry, 2013 , vol. 78, # 3 p. 920 - 934
反应条件
1: pyridine; hydroxylamine hydrochloride / ethanol / 12 h / |Reflux
2: 1,4-diaza-bicyclo[2.2.2]octane / dichloromethane / 12.25 h / -10 - 20 °C / |Microwave irradiation
3: silver tetrafluoroborate; PPh3 gold(I) chloro complex / toluene / 18 h / 100 °C / |Microwave irradiation
View Scheme
参考文献
Ngwerume, Simbarashe; Lewis, William; Camp, Jason E.
Journal of Organic Chemistry, 2013 , vol. 78, # 3 p. 920 - 934
