1: aq. HOAc / tetrahydrofuran / 1.5 h 2: 60 percent / pyridine / tetrahydrofuran / 1.) -30 deg C, 1 h, 2.) 0 deg C, 16 h 3: LiBr / acetone / 2 h / Heating 4: tetrahydrofuran / Heating 5: LDA / tetrahydrofuran / -78 °C 6: Li(sec-Bu)3BH / tetrahydrofuran / -10 °C 7: hexamethylphosphoric acid triamide / 1 h / 110 °C 8: Bu3SnH, AIBN / toluene / 1 h / 60 °C View Scheme