3,5-二叔丁基-4-羟基苯甲醛合成路线 （共 132 条）
反应条件
in dimethyl sulfoxide
T=80°C; 20 h;
参考文献
Katsumi; Kondo; Yamashita; Hidaka; Hosoe; Watanabe
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 1 p. 121 - 129
反应条件
ammonia; sodium
Erwaermen des Reaktionsprodukts mit CH3I in Toluol unter Druck;
参考文献
Cohen
Journal of Organic Chemistry, 1957 , vol. 22, p. 1333
参考文献
Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
Patent: US6335445 B1, 2002 ;
Location in patent: Page column 108 ;
反应条件
sodium borohydride; toluene-4-sulfonic acid in methanol; benzene
参考文献
Chugai Seiyaku, Kabushiki Kaisha
Patent: EP515684 A1, 1992 ;
反应条件
1: toluene / Heating
2: 78.5 percent / NaBH4 / ethanol / 0.5 h / -5 - 0 °C
View Scheme
参考文献
Zeng, Tao; Chen, Ligong; Li, Jiangsheng; Zhang, Yuecheng; Deng, Yi
Journal of Chemical Research, 2006 , # 12 p. 794 - 796
反应条件
1: t-BuOK / acetonitrile / 36 h / 80 °C
2: NaBH4; NaOH / propan-2-ol
View Scheme
参考文献
Shanahan, Charles S.; McGrath, Dominic V.
Journal of Organic Chemistry, 2005 , vol. 70, # 3 p. 1054 - 1056
反应条件
1: NaBH4 / methanol
2: TsCl, Py
View Scheme
参考文献
Teubner,H.-J. et al.
Justus Liebigs Annalen der Chemie, 1978 , p. 757 - 770
反应条件
(i) nBuLi, Me2NCH2CH2NMe2, THF, hexane, (ii) /BRN= 982526/, (iii) aq. HCl; Multistep reaction;
参考文献
Harrer,W. et al.
Tetrahedron, 1975 , vol. 31, p. 625 - 632
反应条件
(NH4)2S2O8; sulfuric acid
T=60°C; Baeyer-Villiger oxidation; 48 h;
参考文献
Barton, Benita; Hoffmann, Petra F.; Zeelie, Bernard
Journal of Chemical Research, Miniprint, 2003 , # 7 p. 729 - 745
反应条件
toluene-4-sulfonic acid in chloroform
Knoevenagel reaction; 21 h; Heating;
参考文献
Hori, Hitoshi; Nagasawa, Hideko; Ishibashi, Masaki; Uto, Yoshihiro; Hirata, Akihiko; Saijo, Kouichi; Ohkura, Kazuto; Kirk, Kenneth L; Uehara, Yoshimasa
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 10 p. 3257 - 3265
