4,7-二氯-6-硝基喹唑啉合成路线 （共 5 条）
反应条件
thionyl chloride; N,N-dimethyl-formamide 1 h; Heating;
参考文献
Bridges; Zhou; Cody; Rewcastle; McMichael; Showalter; Fry; Kraker; Denny
Journal of Medicinal Chemistry, 1996 , vol. 39, # 1 p. 267 - 276
参考文献
US5747498 A1, ;
US 5747498 A
反应条件
1: HNO3; H2SO4 / 80 °C 2: POCl3 / 90 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 4 p. 545 - 548
反应条件
1: 12 N HCl 2: HNO3; H2SO4 / 80 °C 3: POCl3 / 90 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 4 p. 545 - 548
反应条件
1: 2 h / |Reflux 2: sulfuric acid; nitric acid / 50 - 90 °C 3: phosphorus pentachloride / 3 h / 160 °C View Scheme
参考文献
Medicinal Chemistry Research, , vol. 22, # 9 p. 4096 - 4109
