3-(氯甲基)-2-甲氧基吡啶合成路线 （共 3 条）
反应条件
1: With thionyl chloride in dichloromethane T=20°C; 2: With sodium hydrogencarbonate in water 0.0833333 - 0.166667 h;
参考文献
Banner, Bruce Lester; Bilotta, Joseph Anthony; Fotouhi, Nader; Gillespie, Paul; Goodnow, Robert Alan; Hamilton, Matthew Michael; Haynes, Nancy-Ellen; Kowalczyk, Agnieszka; Mayweg, Alexander; Myers, Michael Paul; Pietranico-Cole, Sherrie Lynn; Scott, Nathan Robert; Thakkar, Kshitij Chhabilbhai; Tilley, Jefferson Wright
Patent: US2007/49632 A1, 2007 ;
Location in patent: Page/Page column 38-39 ;
US 20070049632 A1
反应条件
1: DIBAL-H / tetrahydrofuran; hexane / 1 h / 0 °C 2: SOCl2 / CH2Cl2 / 3 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 43, # 18 p. 3386 - 3399
反应条件
1: CHCl3; methanol 2: DIBAL-H / tetrahydrofuran; hexane / 1 h / 0 °C 3: SOCl2 / CH2Cl2 / 3 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 43, # 18 p. 3386 - 3399
