1: 44 percent / dioxane / 24 h / Ambient temperature 2: 2.) sodium methoxide / 1.) anisole, 90 deg C, 1.5 h, 2.) 140 deg C, 35 min 3: 55 percent / NaOMe / 2 h 4: 55 percent / sodium hypochlorite, 1.5 N NaOH / 2.5 h / 75 °C View Scheme

1: water / CH2Cl2 2: 78 percent / sulfuric acid, acetic acid View Scheme

1: 44 percent / dioxane / 24 h / Ambient temperature 2: 2.) sodium methoxide / 1.) anisole, 90 deg C, 1.5 h, 2.) 140 deg C, 35 min 3: 55 percent / NaOMe / 2 h 4: 55 percent / sodium hypochlorite, 1.5 N NaOH / 2.5 h / 75 °C 5: 72 percent / 1.5 N NaOH / 2.5 h / 100 °C View Scheme

water in dichloromethane

1: 1) BSTFA, 2) HgBr2/HgO 2: NH3 / methanol View Scheme

in benzene T=80 - 90°C;